INTRODUCTION
This activity covers the following:
- What volume of distribution is
- The units and symbol for volume of distribution
- A simulation in which you can see the effect of changing volume of distribution
- Uses of volume of distribution and what affects it
- How to find volume of distribution - showing the range of equations available
(including equations using the initial plasma concentration, the elimination rate constant,
clearance, AUC and the steady state concentration)
Before you start
You need to know what area under the concentration-time curve (AUC), clearance and the elimination rate constant are and how to find them.