Introduction To Pharmacokinetics
Area Under The Concentration-Time Curve (AUC)
The simulation on this page plots how the concentration of an example drug changes over time. Change dose and clearance of the drug and see how this affects AUC.
(Assume all other parameters remain the same.)
(Assume all other parameters remain the same.)
Linear Scale
Semilog Scale
Remember:
Dose (D) (0 - 2000 mg)
mg
mg
Clearance (CL) (0 - 90 L h-1)
L h-1 (Remember: CL = k x Vd)
L h-1 (Remember: CL = k x Vd)
Set x-axis (h):
0-12
0-24
0-36
Set y-axis (mg/L): 0-10 0-100 0-1000
Set y-axis (mg/L): 0-10 0-100 0-1000