Pharmacokinetics Simulations
Single Oral Dose - Changing The Elimination Rate Constant
Linear Scale
Semilog Scale
Assumptions:
Dose (D) = 500 mg
Bioavailability (F) = 1
Volume of distribution (V
d
) = 30 L
Absorption rate constant (k
a
) = 1.0 h
-1
Elimination Rate Constant (k)
(0 - 2 h
-1
)
h
-1
Set x-axis (h):
0-12
0-24
0-36
Set y-axis (mg/L):
0-10
0-100
0-1000
Enter values, then
Reset The Simulation