Introduction To Pharmacokinetics

Single Short IV Infusion - Vd

A patient is given a single short IV infusion of 700 mg of a drug over a period of 7 hours.
You now know the following:
t1/2 = 0.5 hours                  k = 1.386 h-1
Css = 4.0 mg                     CL = 25.0 L/h
What is the drug's volume of distribution?
Type in your answer to one decimal places then press the OK button.
The volume of distribution is:   L
Hint/Equation
Time (h) Plasma Drug Concentration (mg/L)
00.0
0.52.0
13.0
1.53.6
23.8
33.9
44.0
54.0
64.0
74.0
7.52.0
81.0
8.50.5
90.25
9.50.13
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