Introduction To Pharmacokinetics

Oral Dosing - k

A patient is given a 500 mg dose of a drug via a single oral dose.
You now know the following:
F = 0.45        t1/2 = 1.5 hours
Now you know the elimination half-life, what is the elimination rate constant (k) of the drug?
Type in your answer to three decimal places then press the OK button.
The elimination rate constant is:   h-1
Time (h) Plasma Drug Concentration (mg/L)
00
0.52.5
13.2
1.53.1
22.8
32.0
41.3
50.8
60.5
70.3
80.2